The Impact of Concurrent Gleptoferron and Toltrazuril Injection on Hematological Profile, Health, and Growth in Pre-weaned Piglets

Abstract

This study sought to assess the effects of simultaneous Gleptoferron and Toltrazuril administration on hematological parameters, health status, and growth performance in pre-weaned piglets. A total of 54 piglets aged 1 to 3 days were randomly allocated into three groups: a control group receiving a placebo injection, a group administered iron (Ferdex), and a group injected with Gleptoferron in conjunction with Toltrazuril (Forceris). Hematological markers, morbidity, mortality, and body weight growth were evaluated during a 20-day duration. The findings indicated that the administration of Gleptoferron and Toltrazuril markedly elevated red blood cell (RBC) counts, hemoglobin concentrations, and hematocrit levels relative to the iron-only group, without an increase in total white blood cell (WBC) counts, suggesting the absence of post-injection infection. Moreover, pigs administered Forceris did not develop hypochromic anemia and had a reduced incidence of diarrhea (6.7%) with no mortality, indicating enhanced gut health and excellent coccidiosis prevention. Significantly, pigs administered Forceris exhibited a weight gain of 9 kg at 20 days of age, in contrast to 7.9 kg in the iron-only cohort. The results indicate that the simultaneous use of Gleptoferron and Toltrazuril provides more advantages in avoiding anemia, improving growth, and fostering better health outcomes in pre-weaned piglets than iron supplementation alone. This efficient and pragmatic approach has significant ramifications for enhancing production in pig breeding operations